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COVERAGE AS OF
APRIL 2021:
1,156,969SAFETY ALERTS
15,271TARGETS & GENES
22,385DRUGS, BIOLOGICS & DRUG COMBINATIONS
10,289ADVERSE EVENTS
COVERAGE AS OF APRIL 2021:
1,156,969
SAFETY ALERTS
15,271
TARGETS & GENES
22,385
DRUGS, BIOLOGICS & DRUG COMBINATIONS
10,289
ADVERSE EVENTS
WEEKLY REPORTS
COVID-19 DAILY ALERTS
SELECTED
DAILY ALERTS
FEATURED
CONGRESS REPORTS
Our editorial team covers more than 500 scientific conferences each year. Select a congress to discover safety insights made public for the first time:
  • SELECTED
    REPORTS
  • UPCOMING
    CONGRESSES
May 13-15
American Geriatrics Society Virtual Annual Scientific Meeting 2021, Virtual
IN PROGRESS
Apr 14-17
12th Annual Meeting of the Clinical Immunology Society (CIS) 2021, Virtual
IN PROGRESS
Apr 10-15
AACR Virtual Annual Meeting 2021 Week 1, Virtual
IN PROGRESS
Apr 7-9
American Burn Association 53rd Annual Meeting 2021, Virtual
Apr 6-10
National Kidney Foundation Spring Clinical Meetings 2021, Virtual
Mar 25-27
European Lung Cancer Congress (ELCC) 2021, Virtual
Mar 25-28
The 140th Annual Meeting of the Pharmaceutical Society of Japan (AMPSJ) 2021, Kyoto
IN PROGRESS
Mar 23-28
25th Anniversary EAHP Congress 2021, Virtual
Mar 20-23
ENDO 2021, Endocrine Society's Annual Meeting, Virtual
Mar 19-25
SGO Annual Meeting on Women's Cancer 2021, Virtual
Mar 17-21
17th St. Gallen International Breast Cancer Conference 2021, Online
Mar 17-19
International Stroke Conference 2021, Virtual
Mar 15-18
MDA Clinical & Scientific Conference 2021, Virtual
Mar 14-17
47th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) 2021, Virtual
Mar 12-26
SOT Annual Meeting and ToxExpo 2021 , Virtual
Mar 10-12
ESMO-The Christie Virtual Preceptorship on Lung Cancer March 2021, Virtual
Mar 9-14
AD/PD 2021 - The 15th International Conference on Alzheimer's & Parkinson's Diseases, Virtual
Mar 8-10
The 94th Annual Meeting of the Japanese Safety Pharmacological Society 2021, Virtual
Mar 6-10
Conference on Retroviruses and Opportunistic Infections (CROI) 2021, Virtual
Mar 5-7
International Society for the Study of Women's Sexual Health (ISSWSH) Annual Meeting 2021, Virtual
Mar 3-6
2nd European Myeloma Network Meeting 2021, Virtual
Mar 1-2
ESMO Targeted Anticancer Therapies (TAT) Virtual Congress 2021, Virtual
Feb 28-Mar 5
AKI & CRRT 2021, Virtual
Feb 26-Mar 1
American Academy of Allergy, Asthma & Immunology (AAAAI) Virtual Annual Meeting 2021, Virtual
Feb 26-28
CINP Virtual World Congress of Neuropsychopharmacology 2021, Virtual
Feb 25-27
18th Annual ENETS Conference 2021, Vitrual
Feb 25-27
ACTRIMS Forum 2021, Virtual
Feb 25-27
Southern Medical Research Conference 2021, Virtual
Feb 22-26
65th Annual Meeting Society of Thrombosis and Haemostasis Research (GTH 2021), Online
Feb 20-24
44th Annual ARO MidWinter Meeting 2021, Virtual
Feb 13-Apr 24
Cardiovascular Research Technologies Conference (CRT) 2021, Virtual
Feb 12-13
ESMO Virtual Summit Africa 2021, Virtual
Feb 11-13
ASCO Genitourinary Cancers Symposium 2021, Virtual
Feb 8-11
AAAS Annual Meeting 2021, Virtual
Feb 8-12
Transplantation and Cellular Therapy Meetings of ASTCT and CIBMTR (TCT) 2021, Virtual
Feb 6-7
The 44th Virtual Annual Macula Society Meeting 2021, Virtual
Feb 5-6
Digital Liver Cancer Summit 2021, Virtual
Feb 5-7
The Medical Dermatology Summit 2021, Virtual
Feb 4-6
30th Annual Conference of Asian Pacific Association for the Study of the Liver (APASL) 2021, Virtual
Feb 3-5
Virtual Congress of the European Association for Haemophilia and Allied Disorders 2021, Virtual
Jan 31-Feb 12
50th Critical Care Congress Virtual Event 2021, Virtual
Jan 28-31
World Conference on Lung Cancer in Singapore IASLC 2020, Virtual
Jan 22-23
ESMO Virtual Preceptorship on Breast Cancer 2021, Virtual
Jan 21-24
Crohn's & Colitis Congress 2021, Virtual
OFF-X ANALYTICS
DATA IN ACTION TO DE-RISK YOUR R&D PROGRAMS
OFF-X is built from the most comprehensive translational safety dataset (1,156,969 curated alerts as of April 2021). We are providing access to a series of analytics and visualization extensions to fully exploit the value of the OFF-X dataset and derive new knowledge. Select your option below and start exploring
OFF-X
ENABLING TRANSLATIONAL SAFETY
By enabling translational research, OFF-X allows safety liabilities to be monitored and anticipated across all phases of drug R&D and post marketing. From target safety assessment to post-marketing signal evaluation, discover the breadth and depth of OFF-X use cases:
Translational Research Teams & Information Professionals
Biologists & Bioinformaticians
Medicinal Chemists
Toxicologists & Safety Pharmacologists
Clinical
Researchers
Pharmacovigilance Professionals
Business Development Executives
Data Scientists
0
Biologists & Bioinformaticians
  • Anticipate safety liabilities of targets entering the pipeline: Target Safety Assessment (TSA)
  • Benchmark target safety profiles across a given indication
  • Build adverse event-based systems toxicology models
Medicinal Chemists
  • Analyze structures to select candidates and optimize lead compounds by identifying toxicophores
  • Compare chemical and pharmacological insights associated to toxicological and safety endpoints
  • Build computational models to predict adverse effects from chemical structures
Toxicologists & Safety Pharmacologists
  • Anticipate and translate to the clinic toxicity and safety events derived from experimental assays and animal models
  • Develop hypotheses for off-target effects (secondary pharmacology profiling) and guide experimental assay planning
  • Determine if an adverse event is compound-related or target-related
  • Stay up-to-date on liabilities associated with a therapeutic target of interest
Clinical Researchers
  • Obtain actionable insights to design first-in-human trials and anticipate safety signals
  • Benchmark the safety profile of compounds as they advance in development
  • Discover mechanisms behind unexpected adverse events observed in a clinical trial
Pharmacovigilance & Patient Safety Professionals
  • Evaluate safety signals that do not appear on a drug's label
  • Compare findings from international regulatory agencies
  • Track & benchmark the evolution of safety evidence over a compound’s or target’s life cycle and compare it with that of others drugs
  • Monitor emerging class liabilities
  • Assess and compare the safety evidence available for a set of targets in a given indication
Business Development Executives
  • Perform safety evidence benchmarking
  • Provide an independent safety risk assessment of licensing opportunities
Data Scientists
  • Expand and integrate expertly curated information with your in-house data
  • Enhance artificial intelligence applications with high quality curated data
  • Improve the performance of predictive analytics
  • Build adverse event-based systems toxicology models
  • Build chemoinformatic models to predict adverse effects from chemical structures
  • Extend the value of your visualization capabilities to better support internal projects
15,271TARGETS & GENES
22,385DRUGS, BIOLOGICS & DRUG COMBINATIONS
1,156,969SAFETY ALERTS
10,289ADVERSE EVENTS
OFF-X API
EMPOWER YOUR INTERNAL SAFETY INTELLIGENCE
Connect to the most comprehensive translational safety data ecosystem through our APIs or data feed licenses. As of April 2021, OFF-X covers More than 15,271 targets, 22,385 drugs and biologics, 10,289 toxicity endpoints and adverse events. Updated daily, the portal is populated with a unique pool of more than 1,156,969 expertly curated safety alerts.

By integrating the OFF-X data with in-house information sources and modeling applications our customers are able to:
  • Enrich and expand the breadth & depth of internal resources coverage
  • Build Artificial Intelligence models with high quality curated data
  • Enhance the performance of predictive analytics
Click here to learn more about OFF-X API (api.targetsafety.info)
OFF-X
NEWS