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COVERAGE AS OF
JUNE 2021:
1,270,377SAFETY ALERTS
15,316TARGETS & GENES
23,208DRUGS, BIOLOGICS & DRUG COMBINATIONS
10,664ADVERSE EVENTS
COVERAGE AS OF JUNE 2021:
1,270,377
SAFETY ALERTS
15,316
TARGETS & GENES
23,208
DRUGS, BIOLOGICS & DRUG COMBINATIONS
10,664
ADVERSE EVENTS
WEEKLY REPORTS
COVID-19 DAILY ALERTS
SELECTED
DAILY ALERTS
FEATURED
CONGRESS REPORTS
Our editorial team covers more than 500 scientific conferences each year. Select a congress to discover safety insights made public for the first time:
  • SELECTED
    REPORTS
  • UPCOMING
    CONGRESSES
Jun 4-8
ASCO Annual Meeting 2021, Virtual
IN PROGRESS
May 14-19
American Thoracic Society (ATS) International Conference 2021, Virtual
May 13-15
46th Annual Regional Anesthesiology and Acute Pain Medicine Meeting 2021, Virtual
May 13-15
American Geriatrics Society Virtual Annual Scientific Meeting 2021, Virtual
May 12-13
ESMO Virtual Plenaries 2021, Virtual
May 12-14
European Network for the Cure of ALS Meeting (ENCALS) 2021, Virtual
May 11-14
24th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT) 2021, Virtual
May 10-12
18th CIMT Annual Meeting 2021, Virtual
May 5-8
ESMO Breast Cancer Virtual Meeting 2021, Virtual
May 3-8
Society for Investigative Dermatology (SID) Virtual Meeting 2021, Virtual
May 1-7
ARVO Virtual Meeting 2021, Virtual
May 1-4
XXVI World Congress on Parkinson’s Disease and Related Disorders (IAPRD) 2021, Virtual
Apr 28-May 1
Society of Biological Psychiatry (SOBP) Virtual Annual Meeting 2021, Virtual
Apr 27-29
16th Annual Huntington's Disease Therapeutics Conference (CHDI) 2021, Virtual
Apr 26-28
British Society for Rheumatology Annual Conference 2021, Virtual
Apr 24-28
41st Annual Meeting and Scientific Sessions ISHLT 2021, Virtual
Apr 23-25
AAD Virtual Meeting Experience (VMX) 2021, Virtual
Apr 20-23
The ASPHO Conference 2021, Virtual
Apr 17-22
Annual Meeting American Academy of Neurology (AAN) 2021, Virtual
Apr 16-17
ESMO Virtual Preceptorship on Colorectal Cancer 2021, Virtual
Apr 15-17
17th EADO Congress & 10th World Congress of Melanoma Interactive Virtual Meeting 2021, Virtual
Apr 15-16
A Scientific Symposium. In celebration of the 100th anniversary of the University of Toronto’s discovery of insulin, Virtual
Apr 15-19
ISN World Congress of Nephrology (WCN) 2021, Virtual
Apr 14-17
12th Annual Meeting of the Clinical Immunology Society (CIS) 2021, Virtual
Apr 13-16
American College of Medical Genetics (ACMG) Annual Meeting 2021, Digital
Apr 12-16
AMCP Virtual 2021, Virtual
Apr 11-14
ESH-ISH Joint Meeting 2021, On Air
Apr 10-13
29th ​European Congress of Psychiatry (EPA) 2021, Virtual
Apr 10-15
AACR Virtual Annual Meeting 2021 Week 1, Virtual
Apr 9-11
53rd Annual Scientific Meeting Australasian College of Dermatologists (ASM53) 2021, Virtual
Apr 7-9
American Burn Association 53rd Annual Meeting 2021, Virtual
Apr 6-10
National Kidney Foundation Spring Clinical Meetings 2021, Virtual
Mar 25-27
European Lung Cancer Congress (ELCC) 2021, Virtual
Mar 25-28
The 140th Annual Meeting of the Pharmaceutical Society of Japan (AMPSJ) 2021, Kyoto
Mar 24-26
Netherlands Ophthalmological Society (NOG) Annual Congress 2021, Virtual
Mar 23-28
25th Anniversary EAHP Congress 2021, Virtual
Mar 20-23
ENDO 2021, Endocrine Society's Annual Meeting, Virtual
OFF-X ANALYTICS
DATA IN ACTION TO DE-RISK YOUR R&D PROGRAMS
OFF-X is built from the most comprehensive translational safety dataset (1,270,377 curated alerts as of June 2021). We are providing access to a series of analytics and visualization extensions to fully exploit the value of the OFF-X dataset and derive new knowledge. Select your option below and start exploring
OFF-X
ENABLING TRANSLATIONAL SAFETY
By enabling translational research, OFF-X allows safety liabilities to be monitored and anticipated across all phases of drug R&D and post marketing. From target safety assessment to post-marketing signal evaluation, discover the breadth and depth of OFF-X use cases:
Translational Research Teams & Information Professionals
Biologists & Bioinformaticians
Medicinal Chemists
Toxicologists & Safety Pharmacologists
Clinical
Researchers
Pharmacovigilance Professionals
Business Development Executives
Data Scientists
0
Biologists & Bioinformaticians
  • Anticipate safety liabilities of targets entering the pipeline: Target Safety Assessment (TSA)
  • Benchmark target safety profiles across a given indication
  • Build adverse event-based systems toxicology models
Medicinal Chemists
  • Analyze structures to select candidates and optimize lead compounds by identifying toxicophores
  • Compare chemical and pharmacological insights associated to toxicological and safety endpoints
  • Build computational models to predict adverse effects from chemical structures
Toxicologists & Safety Pharmacologists
  • Anticipate and translate to the clinic toxicity and safety events derived from experimental assays and animal models
  • Develop hypotheses for off-target effects (secondary pharmacology profiling) and guide experimental assay planning
  • Determine if an adverse event is compound-related or target-related
  • Stay up-to-date on liabilities associated with a therapeutic target of interest
Clinical Researchers
  • Obtain actionable insights to design first-in-human trials and anticipate safety signals
  • Benchmark the safety profile of compounds as they advance in development
  • Discover mechanisms behind unexpected adverse events observed in a clinical trial
Pharmacovigilance & Patient Safety Professionals
  • Evaluate safety signals that do not appear on a drug's label
  • Compare findings from international regulatory agencies
  • Track & benchmark the evolution of safety evidence over a compound’s or target’s life cycle and compare it with that of others drugs
  • Monitor emerging class liabilities
  • Assess and compare the safety evidence available for a set of targets in a given indication
Business Development Executives
  • Perform safety evidence benchmarking
  • Provide an independent safety risk assessment of licensing opportunities
Data Scientists
  • Expand and integrate expertly curated information with your in-house data
  • Enhance artificial intelligence applications with high quality curated data
  • Improve the performance of predictive analytics
  • Build adverse event-based systems toxicology models
  • Build chemoinformatic models to predict adverse effects from chemical structures
  • Extend the value of your visualization capabilities to better support internal projects
15,316TARGETS & GENES
23,208DRUGS, BIOLOGICS & DRUG COMBINATIONS
1,270,377SAFETY ALERTS
10,664ADVERSE EVENTS
OFF-X API
EMPOWER YOUR INTERNAL SAFETY INTELLIGENCE
Connect to the most comprehensive translational safety data ecosystem through our APIs or data feed licenses. As of June 2021, OFF-X covers More than 15,316 targets, 23,208 drugs and biologics, 10,664 toxicity endpoints and adverse events. Updated daily, the portal is populated with a unique pool of more than 1,270,377 expertly curated safety alerts.

By integrating the OFF-X data with in-house information sources and modeling applications our customers are able to:
  • Enrich and expand the breadth & depth of internal resources coverage
  • Build Artificial Intelligence models with high quality curated data
  • Enhance the performance of predictive analytics
Click here to learn more about OFF-X API (api.targetsafety.info)
OFF-X
NEWS