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COVERAGE AS OF
NOVEMBER 2020:
943,457SAFETY ALERTS
15,176TARGETS & GENES
20,613DRUGS, BIOLOGICS & DRUG COMBINATIONS
9,577ADVERSE EVENTS
COVERAGE AS OF NOVEMBER 2020:
943,457
SAFETY ALERTS
15,176
TARGETS & GENES
20,613
DRUGS, BIOLOGICS & DRUG COMBINATIONS
9,577
ADVERSE EVENTS
WEEKLY REPORTS
COVID-19 DAILY ALERTS
FREE ACCESS
SELECTED
DAILY ALERTS
FEATURED
CONGRESS REPORTS
Our editorial team covers more than 500 scientific conferences each year. Select a congress to discover safety insights made public for the first time:
  • SELECTED
    REPORTS
  • UPCOMING
    CONGRESSES
Nov 13-17
American Heart Association's (AHA) 2020 Scientific Sessions, Virtual
IN PROGRESS
Nov 13-15
Fall Clinical Dermatology Conference® for PAs & NPs, Virtual
Nov 9-14
35th Anniversary Annual Meeting SITC 2020, Virtual
Nov 5-9
ACR Convergence 2020, Virtual
IN PROGRESS
Nov 2-6
Obesity Week 2020, Virtual
IN PROGRESS
Oct 24-25
32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutic 2020, Virtual
Oct 23-28
American College of Gastroenterology (ACG) 2020, Virtual
IN PROGRESS
Oct 22-24
47th European Calcified Tissue Society Congress (ECTS) 2020, Digital
Oct 22-24
Kidney Week 2020 Reimagined, Virtual
Oct 21-25
IDWeek 2020, Virtual
Oct 20-23
27th Annual Prostate Cancer Foundation Scientific Retreat 2020, Virtual
Oct 20-24
51st World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease (The Union) 2020, Virtual
Oct 18-21
CHEST Annual Meeting 2020, Virtual Event
Oct 16-17
North America Conference on Lung Cancer 2020, Virtual
Oct 14-17
52nd Congress of the International Society of Paediatric Oncology (SIOP) 2020, Virtual
Oct 12-23
The Joint 16th International Child Neurology Congress & 49th Annual Child Neurology Society Meeting 2020, Virtual
Oct 11-13
UEG Week Virtual 2020, Virtual
Oct 10-11
40th Congress of the Société Internationale d'Urologie - SIU around the World Virtual 2020, Virtual
Oct 7-23
The 34th Annual North American Cystic Fibrosis Conference 2020, Virtual
Oct 5-8
HIV Glasgow 2020, Virtual
Oct 4-9
145th Annual Meeting American Neurological Association 2020, Virtual
Oct 4-7
88th EAS Congress 2020, Virtual
Oct 3-9
MTIS 2020 Virtual Symposium, Virtual
Oct 2-4
Euretina 2020, Virtual
Sep 30-Oct 6
HFSA Virtual Annual Scientific Meeting 2020, Virtual
Sep 28-Oct 2
WMS 2020 Virtual Congress, Virtual
Sep 23-25
26th European Paediatric Rheumatology Congress (PReS 2020), Virtual
Sep 21-25
56th Annual Meeting of the European Association for the Study of Diabetes (EASD 2020), Virtual
Sep 21-23
Annual Meeting of the American College of Clinical Pharmacology (ACCP) 2020, Virtual
Sep 19-21
ESMO 2020 Congress, Virtual
Sep 12-15
33rd ECNP Congress 2020, Virtual
Sep 12-16
MDS Virtual Congress 2020, Virtual
Sep 11-13
8th Joint ACTRIMS-ECTRIMS Meeting 2020, Virtual
Sep 11-15
ASBMR 2020 Annual Meeting, Virtual
Sep 11-13
ILCA 2020 Virtual Conference, Virtual
Sep 10-Dec 10
33rd International Conference on Antiviral Research (ICAR) 2020, Virtual
IN PROGRESS
Sep 10-13
IGCS Annual Global Meeting 2020, Digital
Sep 10-14
North American Congress of Clinical Toxicology (NACCT) 2020, Virtual
Sep 9-12
SOHO 2020 Annual Meeting, Virtual
Sep 7-9
EFMC-ISMC Virtual Event 2020, Virtual
Sep 7-9
European Respiratory Society International Congress (ERS) 2020, Virtual
OFF-X ANALYTICS
DATA IN ACTION TO DE-RISK YOUR R&D PROGRAMS
OFF-X is built from the most comprehensive translational safety dataset (943,457 curated alerts as of November 2020). We are providing access to a series of analytics and visualization extensions to fully exploit the value of the OFF-X dataset and derive new knowledge. Select your option below and start exploring
OFF-X
ENABLING TRANSLATIONAL SAFETY
By enabling translational research, OFF-X allows safety liabilities to be monitored and anticipated across all phases of drug R&D and post marketing. From target safety assessment to post-marketing signal evaluation, discover the breadth and depth of OFF-X use cases:
Translational Research Teams & Information Professionals
Biologists & Bioinformaticians
Medicinal Chemists
Toxicologists & Safety Pharmacologists
Clinical
Researchers
Pharmacovigilance Professionals
Business Development Executives
Data Scientists
0
Biologists & Bioinformaticians
  • Anticipate safety liabilities of targets entering the pipeline: Target Safety Assessment (TSA)
  • Benchmark target safety profiles across a given indication
  • Build adverse event-based systems toxicology models
Medicinal Chemists
  • Analyze structures to select candidates and optimize lead compounds by identifying toxicophores
  • Compare chemical and pharmacological insights associated to toxicological and safety endpoints
  • Build computational models to predict adverse effects from chemical structures
Toxicologists & Safety Pharmacologists
  • Anticipate and translate to the clinic toxicity and safety events derived from experimental assays and animal models
  • Develop hypotheses for off-target effects (secondary pharmacology profiling) and guide experimental assay planning
  • Determine if an adverse event is compound-related or target-related
  • Stay up-to-date on liabilities associated with a therapeutic target of interest
Clinical Researchers
  • Obtain actionable insights to design first-in-human trials and anticipate safety signals
  • Benchmark the safety profile of compounds as they advance in development
  • Discover mechanisms behind unexpected adverse events observed in a clinical trial
Pharmacovigilance & Patient Safety Professionals
  • Evaluate safety signals that do not appear on a drug's label
  • Compare findings from international regulatory agencies
  • Track & benchmark the evolution of safety evidence over a compound’s or target’s life cycle and compare it with that of others drugs
  • Monitor emerging class liabilities
  • Assess and compare the safety evidence available for a set of targets in a given indication
Business Development Executives
  • Perform safety evidence benchmarking
  • Provide an independent safety risk assessment of licensing opportunities
Data Scientists
  • Expand and integrate expertly curated information with your in-house data
  • Enhance artificial intelligence applications with high quality curated data
  • Improve the performance of predictive analytics
  • Build adverse event-based systems toxicology models
  • Build chemoinformatic models to predict adverse effects from chemical structures
  • Extend the value of your visualization capabilities to better support internal projects
15,176TARGETS & GENES
20,613DRUGS, BIOLOGICS & DRUG COMBINATIONS
943,457SAFETY ALERTS
9,577ADVERSE EVENTS
OFF-X API
EMPOWER YOUR INTERNAL SAFETY INTELLIGENCE
Connect to the most comprehensive translational safety data ecosystem through our APIs or data feed licenses. As of November 2020, OFF-X covers More than 15,176 targets, 20,613 drugs and biologics, 9,577 toxicity endpoints and adverse events. Updated daily, the portal is populated with a unique pool of more than 943,457 expertly curated safety alerts.

By integrating the OFF-X data with in-house information sources and modeling applications our customers are able to:
  • Enrich and expand the breadth & depth of internal resources coverage
  • Build Artificial Intelligence models with high quality curated data
  • Enhance the performance of predictive analytics
Click here to learn more about OFF-X API (api.targetsafety.info)
OFF-X
NEWS