COVERAGE AS OF
MAY 2022:
1,603,292SAFETY ALERTS
15,404TARGETS & GENES
28,034DRUGS, BIOLOGICS & DRUG COMBINATIONS
11,318ADVERSE EVENTS
COVERAGE AS OF MAY 2022:
1,603,292
SAFETY ALERTS
15,404
TARGETS & GENES
28,034
DRUGS, BIOLOGICS & DRUG COMBINATIONS
11,318
ADVERSE EVENTS
WEEKLY REPORTS
COVID-19 DAILY ALERTS
SELECTED
DAILY ALERTS
FEATURED
CONGRESS REPORTS
Our editorial team covers more than 500 scientific conferences each year. Select a congress to discover safety insights made public for the first time:
  • SELECTED
    REPORTS
  • UPCOMING
    CONGRESSES
Apr 8-13
AACR Annual Meeting 2022, New Orleans
Apr 2-4
ACC.22 Together With World Congress of Cardiology 2022, Washington
Apr 2-26
Annual Meeting American Academy of Neurology (AAN) 2022, Seattle & Virtual
IN PROGRESS
Mar 30-Apr 2
European Lung Cancer Virtual Congress (ELCC) 2022, Virtual
Mar 27-31
SOT Annual Meeting and ToxExpo 2022, San Diego
Mar 25-29
AAD Annual Meeting 2022, Boston
Mar 25-28
The 142nd Annual Meeting of the Pharmaceutical Society of Japan (AMPSJ) 2022, Nagoya
IN PROGRESS
Mar 24-27
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO IOF-ESCEO) 2022, Virtual
Mar 23-25
26th EAHP Congress 2022, Vienna
Mar 22-26
American College of Medical Genetics (ACMG) 2022, Hybrid
Mar 21-25
35th International Conference on Antiviral Research (ICAR) 2022, Seattle & Online
Mar 19-23
48th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) 2022, Virtual
IN PROGRESS
Mar 19-24
USCAP 111th Annual Meeting 2022, Los Angeles
Mar 18-19
Acute Cardiovascular Care 2022, Online
Mar 17-20
ECNP Workshop for Early Career Scientists in Europe 2022, Nice
Mar 16-18
American Society for Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting 2022, Online
Mar 15-19
69th Society for Reproductive Investigation (SRI) Annual Scientific Meeting 2022, Denver
Mar 15-20
AD/PD 2022 - The 16th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona
Mar 13-16
MDA Clinical & Scientific Conference 2022, Nashville
Mar 11-16
World Sleep Congress 2022, Rome
Mar 10-11
19th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease 2022, Hybrid
Mar 7-8
ESMO Targeted Anticancer Therapies (TAT) Virtual Congress 2022, Virtual
Mar 6-9
14th International Gastric Cancer Congress (IGCC) 2022, Houston
Mar 1-4
66th Annual Meeting Society of Thrombosis and Haemostasis Research (GTH 2022), Leipzig
Feb 28-Mar 3
17th Annual Huntington's Disease Therapeutics Conference (CHDI) 2022, Palm Springs
Feb 25-28
American Academy of Allergy, Asthma & Immunology (AAAAI) Virtual Annual Meeting 2022, Phoenix
Feb 24-26
ACTRIMS Forum 2022, West Palm Beach
Feb 24-27
ISN World Congress of Nephrology (WCN) 2022, Kuala Lumpur
Feb 24-26
Multidisciplinary Head and Neck Cancer Symposium 2022, Phoenix
Feb 22-26
IASLC Targeted Therapies of Lung Cancer Meeting (TTLC) 2022, Virtual
Feb 17-19
ASCO Genitourinary Cancers Symposium 2022, Virtual
Feb 16-19
17th Congress of ECCO 2022, Virtual
OFF-X ANALYTICS
DATA IN ACTION TO DE-RISK YOUR R&D PROGRAMS
OFF-X is built from the most comprehensive translational safety dataset (1,603,292 curated alerts as of May 2022). We are providing access to a series of analytics and visualization extensions to fully exploit the value of the OFF-X dataset and derive new knowledge. Select your option below and start exploring
OFF-X
ENABLING TRANSLATIONAL SAFETY
By enabling translational research, OFF-X allows safety liabilities to be monitored and anticipated across all phases of drug R&D and post marketing. From target safety assessment to post-marketing signal evaluation, discover the breadth and depth of OFF-X use cases:
Translational Research Teams & Information Professionals
Biologists & Bioinformaticians
Medicinal Chemists
Toxicologists & Safety Pharmacologists
Clinical
Researchers
Pharmacovigilance Professionals
Business Development Executives
Data Scientists
0
Biologists & Bioinformaticians
  • Anticipate safety liabilities of targets entering the pipeline: Target Safety Assessment (TSA)
  • Benchmark target safety profiles across a given indication
  • Build adverse event-based systems toxicology models
Medicinal Chemists
  • Analyze structures to select candidates and optimize lead compounds by identifying toxicophores
  • Compare chemical and pharmacological insights associated to toxicological and safety endpoints
  • Build computational models to predict adverse effects from chemical structures
Toxicologists & Safety Pharmacologists
  • Anticipate and translate to the clinic toxicity and safety events derived from experimental assays and animal models
  • Develop hypotheses for off-target effects (secondary pharmacology profiling) and guide experimental assay planning
  • Determine if an adverse event is compound-related or target-related
  • Stay up-to-date on liabilities associated with a therapeutic target of interest
Clinical Researchers
  • Obtain actionable insights to design first-in-human trials and anticipate safety signals
  • Benchmark the safety profile of compounds as they advance in development
  • Discover mechanisms behind unexpected adverse events observed in a clinical trial
Pharmacovigilance & Patient Safety Professionals
  • Evaluate safety signals that do not appear on a drug's label
  • Compare findings from international regulatory agencies
  • Track & benchmark the evolution of safety evidence over a compound’s or target’s life cycle and compare it with that of others drugs
  • Monitor emerging class liabilities
  • Assess and compare the safety evidence available for a set of targets in a given indication
Business Development Executives
  • Perform safety evidence benchmarking
  • Provide an independent safety risk assessment of licensing opportunities
Data Scientists
  • Expand and integrate expertly curated information with your in-house data
  • Enhance artificial intelligence applications with high quality curated data
  • Improve the performance of predictive analytics
  • Build adverse event-based systems toxicology models
  • Build chemoinformatic models to predict adverse effects from chemical structures
  • Extend the value of your visualization capabilities to better support internal projects
15,404TARGETS & GENES
28,034DRUGS, BIOLOGICS & DRUG COMBINATIONS
1,603,292SAFETY ALERTS
11,318ADVERSE EVENTS
OFF-X API
EMPOWER YOUR INTERNAL SAFETY INTELLIGENCE
Connect to the most comprehensive translational safety data ecosystem through our APIs or data feed licenses. As of May 2022, OFF-X covers More than 15,404 targets, 28,034 drugs and biologics, 11,318 toxicity endpoints and adverse events. Updated daily, the portal is populated with a unique pool of more than 1,603,292 expertly curated safety alerts.

By integrating the OFF-X data with in-house information sources and modeling applications our customers are able to:
  • Enrich and expand the breadth & depth of internal resources coverage
  • Build Artificial Intelligence models with high quality curated data
  • Enhance the performance of predictive analytics
Click here to learn more about OFF-X API (api.targetsafety.info)